Thisunusual dual membrane -certain topology of tetherin led to several models, involving extended or laterally arranged parallel or anti-parallel protein dimers in the cell surface, to explain virus tethering 131, and a number of recent X-ray crystal structures revealed the ectodomain indeed forms a parallel dimeric helical coiled coil 135C137 - Current concepts in The identification and characterisation of Rho Kinase Inhibitors

Thisunusual dual membrane -certain topology of tetherin led to several models, involving extended or laterally arranged parallel or anti-parallel protein dimers in the cell surface, to explain virus tethering 131, and a number of recent X-ray crystal structures revealed the ectodomain indeed forms a parallel dimeric helical coiled coil 135C137. the development of fresh therapeutics. … Continue reading Thisunusual dual membrane -certain topology of tetherin led to several models, involving extended or laterally arranged parallel or anti-parallel protein dimers in the cell surface, to explain virus tethering 131, and a number of recent X-ray crystal structures revealed the ectodomain indeed forms a parallel dimeric helical coiled coil 135C137